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Chemical structure of MK-4074

GC31344

MK-4074

Also known as 5-[1'-(1-cyclopropyl-4-methoxy-3-methylindole-6-carbonyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl]pyridine-3-carboxylic acid

MK-4074 is a liver-specific inhibitor of acetyl-CoA carboxylase ACC1 and ACC2 with IC50 values of approximately 3 nM

ChemicalCAS1039758-22-9MW565.62FormulaC33H31N3O6
CAS number
1039758-22-9
Molecular weight
565.62
Formula
C33H31N3O6
Solubility
DMSO ： 83·3 mg/mL (147·27 mM)
InChIKey
WDBNGXLHMZSUEI-UHFFFAOYSA-N
Catalogue number
GC31344
Brand
GLPBIO
Computed properties PubChem CID 24964679 · XLogP 3.9 · TPSA 111 Ų · H-bond donors 1
XLogP
3.9
TPSA
111 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
42

SMILES CC1=CN(C2=C1C(=CC(=C2)C(=O)N3CCC4(CC3)CC(=O)C5=C(O4)C=CC(=C5)C6=CC(=CN=C6)C(=O)O)OC)C7CC7

Computed descriptors from PubChem (CID 24964679), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.