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Chemical structure of MK-3697

GC19250

MK-3697

Also known as N-[(5,6-dimethoxy-2-pyridinyl)methyl]-2-(5-methyl-3-pyridinyl)-5-(1,3-thiazol-2-yl)pyridine-4-carboxamide

MK-3697 is an isonicotinamide small molecule, acting as a potent and selective Orexin 2 receptor antagonist with Ki = 0·95 nM

ChemicalCAS1224846-01-8MW447.51FormulaC23H21N5O3S
CAS number
1224846-01-8
Molecular weight
447.51
Formula
C23H21N5O3S
Solubility
DMSO ： 22·5 mg/mL (50·28 mM)
InChIKey
VSOUDUXMPUHJEU-UHFFFAOYSA-N
Catalogue number
GC19250
Brand
GLPBIO
Computed properties PubChem CID 46190695 · XLogP 2.5 · TPSA 127 Ų · H-bond donors 1
XLogP
2.5
TPSA
127 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
7
Heavy atoms
32

SMILES CC1=CC(=CN=C1)C2=NC=C(C(=C2)C(=O)NCC3=NC(=C(C=C3)OC)OC)C4=NC=CS4

Computed descriptors from PubChem (CID 46190695), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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