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Chemical structure of L791943

GC31258

L791943

Also known as 2-[4-[1-[3,4-bis(difluoromethoxy)phenyl]-2-(1-oxidopyridin-1-ium-4-yl)ethyl]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol

L791943 is a potent, selective Phosphodiesterase-4 (PDE4) inhibitor with an IC50 of 4·2 nM

ChemicalCAS192767-01-4MW573.38FormulaC24H17F10NO4
CAS number
192767-01-4
Molecular weight
573.38
Formula
C24H17F10NO4
Solubility
Soluble in DMSO
InChIKey
VIOWRSXFEPSZFI-UHFFFAOYSA-N
Catalogue number
GC31258
Brand
GLPBIO
Computed properties PubChem CID 9808191 · XLogP 6.6 · TPSA 64.2 Ų · H-bond donors 1
XLogP
6.6
TPSA
64.2 Ų
H-bond donors
1
H-bond acceptors
14
Rotatable bonds
9
Heavy atoms
39

SMILES C1=CC(=CC=C1C(CC2=CC=[N+](C=C2)[O-])C3=CC(=C(C=C3)OC(F)F)OC(F)F)C(C(F)(F)F)(C(F)(F)F)O

Computed descriptors from PubChem (CID 9808191), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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