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Chemical structure of L67

GC18186

L67

Also known as 2-(3,5-dibromo-4-methylanilino)-N-[(E)-(2-hydroxy-5-nitrophenyl)methylideneamino]acetamide

L67 is a competitive inhibitor of DNA ligases I and III (IC50s = 10 and 10 uM for human DNA ligase I and human ligase IIIβ)

ChemicalCAS325970-71-6MW486.1FormulaC16H14Br2N4O4
CAS number
325970-71-6
Molecular weight
486.1
Formula
C16H14Br2N4O4
Solubility
DMF： 10 mg/ml,DMSO： 10 mg/ml
InChIKey
KFEPVFJQVOMODD-IFRROFPPSA-N
Catalogue number
GC18186
Brand
GLPBIO
Computed properties PubChem CID 135419707 · XLogP 4.1 · TPSA 120 Ų · H-bond donors 3
XLogP
4.1
TPSA
120 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
26

SMILES CC1=C(C=C(C=C1Br)NCC(=O)N/N=C/C2=C(C=CC(=C2)[N+](=O)[O-])O)Br

Computed descriptors from PubChem (CID 135419707), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.