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Chemical structure of AVN-492

GC30907

AVN-492

Also known as 3-(benzenesulfonyl)-2-N,6-N,6-N,5,7-pentamethylpyrazolo[1,5-a]pyrimidine-2,6-diamine

AVN-492 is a very specific and highly-selective antagonist with picomolar affinity to 5-HT6R (Ki=91 pM)

ChemicalCAS1220646-23-0MW359.45FormulaC17H21N5O2S
CAS number
1220646-23-0
Molecular weight
359.45
Formula
C17H21N5O2S
Solubility
DMSO : ≥ 100 mg/mL (278·20 mM)
InChIKey
SNPPEHMSSOEYDH-UHFFFAOYSA-N
Catalogue number
GC30907
Brand
GLPBIO
Computed properties PubChem CID 56655571 · XLogP 2.9 · TPSA 88 Ų · H-bond donors 1
XLogP
2.9
TPSA
88 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
25

SMILES CC1=C(C(=NC2=C(C(=NN12)NC)S(=O)(=O)C3=CC=CC=C3)C)N(C)C

Computed descriptors from PubChem (CID 56655571), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
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