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Chemical structure of AVN-944

GC19045

AVN-944

Also known as [(2R)-1-cyanobutan-2-yl] N-[(1S)-1-[3-[[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]carbamoylamino]phenyl]ethyl]carbamate

AVN-944(VX-944) is a selective, noncompetitive inhibitor of the enzyme directed against human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2

ChemicalCAS297730-17-7MW477.51FormulaC25H27N5O5
CAS number
297730-17-7
Molecular weight
477.51
Formula
C25H27N5O5
Solubility
DMSO ： ≥ 31 mg/mL (64·92 mM)
InChIKey
GYCPCOJTCINIFZ-OXJNMPFZSA-N
Catalogue number
GC19045
Brand
GLPBIO
Computed properties PubChem CID 9918559 · XLogP 3.1 · TPSA 139 Ų · H-bond donors 3
XLogP
3.1
TPSA
139 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
10
Heavy atoms
35

SMILES CC[C@H](CC#N)OC(=O)N[C@@H](C)C1=CC(=CC=C1)NC(=O)NC2=CC(=C(C=C2)C3=CN=CO3)OC

Computed descriptors from PubChem (CID 9918559), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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