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Chemical structure of TRPM8 Antagonist

GC30893

TRPM8 Antagonist

Also known as methyl (2S)-2-(dibenzylamino)-3-(1H-indol-3-yl)propanoate

TRPM8 Antagonist is a potent and selective TRPM8 antagonist, with an IC50 of 0·2 nM, used in the research of neuropathic pain syndromes

ChemicalCAS259674-19-6MW398.5FormulaC26H26N2O2
CAS number
259674-19-6
Molecular weight
398.5
Formula
C26H26N2O2
Solubility
DMSO : 160 mg/mL (401·51 mM)
InChIKey
HHVOOJDLCVOLKI-VWLOTQADSA-N
Catalogue number
GC30893
Brand
GLPBIO
Computed properties PubChem CID 57055437 · XLogP 5.5 · TPSA 45.3 Ų · H-bond donors 1
XLogP
5.5
TPSA
45.3 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
9
Heavy atoms
30

SMILES COC(=O)[C@H](CC1=CNC2=CC=CC=C21)N(CC3=CC=CC=C3)CC4=CC=CC=C4

Computed descriptors from PubChem (CID 57055437), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
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