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Chemical structure of JNJ-40411813 (ADX-71149)

GC30819

JNJ-40411813 (ADX-71149)

Also known as 1-butyl-3-chloro-4-(4-phenylpiperidin-1-yl)pyridin-2-one

JNJ-40411813 (ADX-71149) (ADX-71149) is a novel positive allosteric modulator of the metabotropic Glutamate 2 receptor (mGlu2R) with EC50 of 147 nM

ChemicalCAS1127498-03-6MW344.88FormulaC20H25ClN2O
CAS number
1127498-03-6
Molecular weight
344.88
Formula
C20H25ClN2O
Solubility
DMSO : 25 mg/mL (72·49 mM)
InChIKey
HYOGJHCDLQSAHX-UHFFFAOYSA-N
Catalogue number
GC30819
Brand
GLPBIO
Computed properties PubChem CID 25195461 · XLogP 4.6 · TPSA 23.6 Ų · H-bond donors 0
XLogP
4.6
TPSA
23.6 Ų
H-bond donors
0
H-bond acceptors
2
Rotatable bonds
5
Heavy atoms
24

SMILES CCCCN1C=CC(=C(C1=O)Cl)N2CCC(CC2)C3=CC=CC=C3

Computed descriptors from PubChem (CID 25195461), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.