
GC30819
JNJ-40411813 (ADX-71149)
Also known as 1-butyl-3-chloro-4-(4-phenylpiperidin-1-yl)pyridin-2-one
JNJ-40411813 (ADX-71149) (ADX-71149) is a novel positive allosteric modulator of the metabotropic Glutamate 2 receptor (mGlu2R) with EC50 of 147 nM
ChemicalCAS1127498-03-6MW344.88FormulaC20H25ClN2O
- CAS number
- 1127498-03-6
- Molecular weight
- 344.88
- Formula
- C20H25ClN2O
- Solubility
- DMSO : 25 mg/mL (72·49 mM)
- InChIKey
- HYOGJHCDLQSAHX-UHFFFAOYSA-N
- Catalogue number
- GC30819
- Brand
- GLPBIO
Computed properties PubChem CID 25195461 · XLogP 4.6 · TPSA 23.6 Ų · H-bond donors 0
- XLogP
- 4.6
- TPSA
- 23.6 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Rotatable bonds
- 5
- Heavy atoms
- 24
SMILES CCCCN1C=CC(=C(C1=O)Cl)N2CCC(CC2)C3=CC=CC=C3
Computed descriptors from PubChem (CID 25195461), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il