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Chemical structure of SIRT5 inhibitor

GC30251

SIRT5 inhibitor

Also known as 3-[[(5S)-6-[[(2S)-1-(cyclobutylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(3-fluorophenyl)sulfonylamino]-6-oxohexyl]carbamothioylamino]propanoic acid

SIRT5 inhibitor is a potent Human Sirtuin 5 deacylase inhibitor, with an IC50 of 0·11 μM

ChemicalCAS2166487-21-2MW674.81FormulaC31H39FN6O6S2
CAS number
2166487-21-2
Molecular weight
674.81
Formula
C31H39FN6O6S2
Solubility
DMSO : 125 mg/mL (185·24 mM)
InChIKey
NEJMWPNVCQYZKG-SVBPBHIXSA-N
Catalogue number
GC30251
Brand
GLPBIO
Computed properties PubChem CID 134828254 · XLogP 3.1 · TPSA 222 Ų · H-bond donors 7
XLogP
3.1
TPSA
222 Ų
H-bond donors
7
H-bond acceptors
9
Rotatable bonds
17
Heavy atoms
46

SMILES C1CC(C1)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)[C@H](CCCCNC(=S)NCCC(=O)O)NS(=O)(=O)C4=CC=CC(=C4)F

Computed descriptors from PubChem (CID 134828254), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.