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Chemical structure of SC-1

GC25899

SC-1

Also known as 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[4-(4-cyanophenoxy)phenyl]urea

SC-1 (1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea, STAT3-IN-7), a Sorafenib analogue and potently inhibits the phosphorylation of STAT3, induces cell apoptosis through SHP-1 dependent STAT3 inactivation

ChemicalCAS1313019-65-6MW431.8FormulaC21H13ClF3N3O2
CAS number
1313019-65-6
Molecular weight
431.8
Formula
C21H13ClF3N3O2
Solubility
DMSO： 86 mg/mL (199·17 mM);Water： Insoluble;Ethanol： 86 mg/mL (199·17 mM)
InChIKey
HVPZDXDXIQZKHU-UHFFFAOYSA-N
Catalogue number
GC25899
Brand
GLPBIO
Computed properties PubChem CID 53327725 · XLogP 6 · TPSA 74.2 Ų · H-bond donors 2
XLogP
6
TPSA
74.2 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
30

SMILES C1=CC(=CC=C1C#N)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F

Computed descriptors from PubChem (CID 53327725), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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