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Chemical structure of SB 200646

GC25898

SB 200646

Also known as 1-(1-methylindol-5-yl)-3-pyridin-3-ylurea

SB 200646 (SB 200646A) is a potent, selective and oral-active antagonist of 5-HT2B/2C over 5-HT2A receptor with 50 fold selectivity· The pKi for rat 5-HT2C receptor, rat 5-HT2B receptor and rat 5-HT2A receptor are 6·9, 7·5 and 5·2, respectively· SB 200646 has electrophysiological and anxiolytic properties in vivo

ChemicalCAS143797-63-1MW266.3FormulaC15H14N4O
CAS number
143797-63-1
Molecular weight
266.3
Formula
C15H14N4O
Solubility
DMSO： 53 mg/mL (199·02 mM);Water： ?1 mg/mL (NaN mM);Ethanol： 2 mg/mL (7·51 mM)
InChIKey
OJZZJTLBYXHUSJ-UHFFFAOYSA-N
Catalogue number
GC25898
Brand
GLPBIO
Computed properties PubChem CID 126769 · XLogP 1.5 · TPSA 59 Ų · H-bond donors 2
XLogP
1.5
TPSA
59 Ų
H-bond donors
2
H-bond acceptors
2
Rotatable bonds
2
Heavy atoms
20

SMILES CN1C=CC2=C1C=CC(=C2)NC(=O)NC3=CN=CC=C3

Computed descriptors from PubChem (CID 126769), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.