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Chemical structure of SB 203580 hydrochloride

GC13001

SB 203580 hydrochloride

Also known as 4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine;hydrochloride

Adezmapimod (SB 203580) hydrochloride is a selective and ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38β2, respectively

ChemicalCAS869185-85-3MW413.9FormulaC21H17ClFN3OS
CAS number
869185-85-3
Molecular weight
413.9
Formula
C21H17ClFN3OS
Solubility
≥ 20·7mg/mL in DMSO
InChIKey
WOSGGXINSLMASH-UHFFFAOYSA-N
Catalogue number
GC13001
Brand
GLPBIO
Computed properties PubChem CID 16760644 · TPSA 77.9 Ų · H-bond donors 2 · H-bond acceptors 5
TPSA
77.9 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
28

SMILES CS(=O)C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F.Cl

Computed descriptors from PubChem (CID 16760644), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.