
GC25869
RO495
Also known as N-[2-[(2-amino-6-methylpyrimidin-4-yl)amino]-4-pyridinyl]-2,6-dichlorobenzamide
RO495 (CS-2667) is a potent inhibitor of Non-receptor tyrosine-protein kinase 2 (TYK2)
ChemicalCAS1258296-60-4MW389.24FormulaC17H14Cl2N6O
- CAS number
- 1258296-60-4
- Molecular weight
- 389.24
- Formula
- C17H14Cl2N6O
- Solubility
- DMSO: 78 mg/mL (200·39 mM);Water: Insoluble;Ethanol: Insoluble
- InChIKey
- LNGDQKGREFSTHB-UHFFFAOYSA-N
- Catalogue number
- GC25869
- Brand
- GLPBIO
Computed properties PubChem CID 57519505 · XLogP 3.5 · TPSA 106 Ų · H-bond donors 3
- XLogP
- 3.5
- TPSA
- 106 Ų
- H-bond donors
- 3
- H-bond acceptors
- 6
- Rotatable bonds
- 4
- Heavy atoms
- 26
SMILES CC1=CC(=NC(=N1)N)NC2=NC=CC(=C2)NC(=O)C3=C(C=CC=C3Cl)Cl
Computed descriptors from PubChem (CID 57519505), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il