GC25160
BMS-1001
Also known as (2R)-2-[[2-[(3-cyanophenyl)methoxy]-4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]methoxy]-5-methylphenyl]methylamino]-3-hydroxypropanoic acid
BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction with EC50 of 253 nM· BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes
ChemicalCAS2113650-03-4MW594.65FormulaC35H34N2O7
- CAS number
- 2113650-03-4
- Molecular weight
- 594.65
- Formula
- C35H34N2O7
- Solubility
- DMSO： 50 mg/mL (84·08 mM);Water： Insoluble;Ethanol： Insoluble
- InChIKey
- UWNXGZKSIKQKAH-SSEXGKCCSA-N
- Catalogue number
- GC25160
- Brand
- GLPBIO
Computed properties PubChem CID 131839624 · XLogP 2.7 · TPSA 130 Ų · H-bond donors 3
- XLogP
- 2.7
- TPSA
- 130 Ų
- H-bond donors
- 3
- H-bond acceptors
- 9
- Rotatable bonds
- 12
- Heavy atoms
- 44
SMILES CC1=CC(=C(C=C1OCC2=C(C(=CC=C2)C3=CC4=C(C=C3)OCCO4)C)OCC5=CC(=CC=C5)C#N)CN[C@H](CO)C(=O)O
Computed descriptors from PubChem (CID 131839624), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il