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Chemical structure of BMS-3

GC19076

BMS-3

Also known as N-[5-[1-(2,6-dichlorophenyl)-3-(difluoromethyl)pyrazol-5-yl]-1,3-thiazol-2-yl]cyclopropanecarboxamide

BMS-3 is a potent LIMK inhibitor with IC50s of 5 nM and 6 nM for LIMK1 and LIMK2, respectively

ChemicalCAS1338247-30-5MW429.27FormulaC17H12Cl2F2N4OS
CAS number
1338247-30-5
Molecular weight
429.27
Formula
C17H12Cl2F2N4OS
Solubility
DMSO : ≥ 30 mg/mL (69·89 mM)
InChIKey
YBGGBHCJSAEIAS-UHFFFAOYSA-N
Catalogue number
GC19076
Brand
GLPBIO
Computed properties PubChem CID 73265272 · XLogP 4.5 · TPSA 88.1 Ų · H-bond donors 1
XLogP
4.5
TPSA
88.1 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
27

SMILES C1CC1C(=O)NC2=NC=C(S2)C3=CC(=NN3C4=C(C=CC=C4Cl)Cl)C(F)F

Computed descriptors from PubChem (CID 73265272), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
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