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Chemical structure of TVB-3664

GC19976

TVB-3664

Also known as 4-[1-[5-[5-(methoxymethyl)-2-(trifluoromethyl)-1H-imidazol-4-yl]-2,4-dimethylbenzoyl]azetidin-3-yl]benzonitrile

TVB-3664 is an orally active fatty acid synthase (FASN) inhibitor with IC50 values of 18 nM and 12 nM for human and mouse FASN, respectively

ChemicalCAS2097262-58-1MW468.47FormulaC25H23F3N4O2
CAS number
2097262-58-1
Molecular weight
468.47
Formula
C25H23F3N4O2
Solubility
DMSO : 10 mg/mL (21·35 mM; Need ultrasonic)
InChIKey
YFEOVRCUSPPGFZ-UHFFFAOYSA-N
Catalogue number
GC19976
Brand
GLPBIO
Computed properties PubChem CID 129101638 · XLogP 3.8 · TPSA 82 Ų · H-bond donors 1
XLogP
3.8
TPSA
82 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
34

SMILES CC1=CC(=C(C=C1C2=C(NC(=N2)C(F)(F)F)COC)C(=O)N3CC(C3)C4=CC=C(C=C4)C#N)C

Computed descriptors from PubChem (CID 129101638), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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