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Chemical structure of TUL01101

GC75465

TUL01101

Also known as N-[5-[2-[(1S)-2,2-difluorocyclopropanecarbonyl]-2-azaspiro[3.5]nonan-7-yl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide

TUL01101 is a potent, selective and orally active JAK1 inhibitor, with an IC50s of 3, 37, 1517 and 36 nM for JAK1, JAK2, JAK3, and TYK2, respectively

ChemicalCAS2411222-97-2MW429.46FormulaC22H25F2N5O2
CAS number
2411222-97-2
Molecular weight
429.46
Formula
C22H25F2N5O2
Solubility
DMSO： ≥ 200 mg/mL (465·70 mM)
InChIKey
ZOUHWHPRPDJDQE-HNNXBMFYSA-N
Catalogue number
GC75465
Brand
GLPBIO
Computed properties PubChem CID 146408604 · XLogP 2.2 · TPSA 79.6 Ų · H-bond donors 1
XLogP
2.2
TPSA
79.6 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
31

SMILES C1CC1C(=O)NC2=NN3C(=N2)C=CC=C3C4CCC5(CC4)CN(C5)C(=O)[C@@H]6CC6(F)F

Computed descriptors from PubChem (CID 146408604), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.