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Chemical structure of TGFβRI-IN-3

GC19911

TGFβRI-IN-3

Also known as N-[2-(3-methylphenyl)-4-pyridinyl]-7-(4-methylsulfonylphenyl)quinolin-4-amine

TGFβRI-IN-3 inhibits TGFβR1 at an IC50 of 0·79 nM with 2000-fold selectivity against MAP4K4

ChemicalCAS2763602-67-9MW465.57FormulaC28H23N3O2S
CAS number
2763602-67-9
Molecular weight
465.57
Formula
C28H23N3O2S
Solubility
DMSO ： 50 mg/mL (107·40 mM; ultrasonic and warming and heat to 60°C)
InChIKey
VYDDFPZEAIUBBH-UHFFFAOYSA-N
Catalogue number
GC19911
Brand
GLPBIO
Computed properties PubChem CID 162640856 · XLogP 5.6 · TPSA 80.3 Ų · H-bond donors 1
XLogP
5.6
TPSA
80.3 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
5
Heavy atoms
34

SMILES CC1=CC(=CC=C1)C2=NC=CC(=C2)NC3=C4C=CC(=CC4=NC=C3)C5=CC=C(C=C5)S(=O)(=O)C

Computed descriptors from PubChem (CID 162640856), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.