Loading...
Chemical structure of Sitravatinib

GC19332

Sitravatinib

Also known as 1-N'-[3-fluoro-4-[2-[5-[(2-methoxyethylamino)methyl]-2-pyridinyl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

Sitravatinib is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth with IC50 of 3980 nmol/L

ChemicalCAS1123837-84-2MW629.68FormulaC33H29F2N5O4S
CAS number
1123837-84-2
Molecular weight
629.68
Formula
C33H29F2N5O4S
Solubility
DMSO ： ≥ 32 mg/mL (50·82 mM)
InChIKey
WLAVZAAODLTUSW-UHFFFAOYSA-N
Catalogue number
GC19332
Brand
GLPBIO
Computed properties PubChem CID 25212148 · XLogP 5.2 · TPSA 143 Ų · H-bond donors 3
XLogP
5.2
TPSA
143 Ų
H-bond donors
3
H-bond acceptors
10
Rotatable bonds
12
Heavy atoms
45

SMILES COCCNCC1=CN=C(C=C1)C2=CC3=NC=CC(=C3S2)OC4=C(C=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F

Computed descriptors from PubChem (CID 25212148), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.