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Chemical structure of IPI549

GC19202

IPI549

Also known as 2-amino-N-[(1S)-1-[8-[2-(1-methylpyrazol-4-yl)ethynyl]-1-oxo-2-phenylisoquinolin-3-yl]ethyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

IPI549 (IPI549) is a potent and selective PI3Kγ inhibitor with an IC50 of 16 nM· IPI549 shows >100-fold selectivity over other lipid and protein kinases

ChemicalCAS1693758-51-8MW528.56FormulaC30H24N8O2
CAS number
1693758-51-8
Molecular weight
528.56
Formula
C30H24N8O2
Solubility
DMSO ： 15 mg/mL (28·38 mM)
InChIKey
XUMALORDVCFWKV-IBGZPJMESA-N
Catalogue number
GC19202
Brand
GLPBIO
Computed properties PubChem CID 91933883 · XLogP 3.2 · TPSA 123 Ų · H-bond donors 2
XLogP
3.2
TPSA
123 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
40

SMILES C[C@@H](C1=CC2=C(C(=CC=C2)C#CC3=CN(N=C3)C)C(=O)N1C4=CC=CC=C4)NC(=O)C5=C6N=CC=CN6N=C5N

Computed descriptors from PubChem (CID 91933883), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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