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Chemical structure of Duvelisib

GC10749

Duvelisib

Also listed as IPI-145 (INK1197)

IPI-145 (INK1197) (IPI-145) is a selectivite p100δ inhibitor with IC50 of 2·5 nM, 27·4 nM, 85 nM and 1602 nM for p110δ, P110γ, p110β and p110α, respectively

ChemicalCAS1201438-56-3MW416.86FormulaC22H17ClN6O
CAS number
1201438-56-3
Molecular weight
416.86
Formula
C22H17ClN6O
Solubility
≥ 20·843mg/mL in DMSO
InChIKey
SJVQHLPISAIATJ-ZDUSSCGKSA-N
Catalogue number
GC10749
Brand
GLPBIO
Computed properties PubChem CID 50905713 · XLogP 4.1 · TPSA 86.8 Ų · H-bond donors 2
XLogP
4.1
TPSA
86.8 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
30

SMILES C[C@@H](C1=CC2=C(C(=CC=C2)Cl)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5

Computed descriptors from PubChem (CID 50905713), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.