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Chemical structure of GSK583

GC19185

GSK583

Also known as 6-tert-butylsulfonyl-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine

GSK583 is a highly potent and selective inhibitor of RIP2 Kinase, with IC50 of 5 nM

ChemicalCAS1346547-00-9MW398.45FormulaC20H19FN4O2S
CAS number
1346547-00-9
Molecular weight
398.45
Formula
C20H19FN4O2S
Solubility
DMSO ： ≥ 37 mg/mL (92·86 mM)
InChIKey
XLOGLWKOHPIJLV-UHFFFAOYSA-N
Catalogue number
GC19185
Brand
GLPBIO
Computed properties PubChem CID 67469084 · XLogP 4 · TPSA 96.1 Ų · H-bond donors 2
XLogP
4
TPSA
96.1 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
28

SMILES CC(C)(C)S(=O)(=O)C1=CC2=C(C=CN=C2C=C1)NC3=NNC4=C3C=C(C=C4)F

Computed descriptors from PubChem (CID 67469084), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.