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Chemical structure of AF38469

GC19023

AF38469

Also known as 2-[(6-methyl-2-pyridinyl)carbamoyl]-5-(trifluoromethyl)benzoic acid

AF38469 is a novel, selective, orally bioavailable Sortilin inhibitor with an IC50 value of 330 nM

ChemicalCAS1531634-31-7MW324.25FormulaC15H11F3N2O3
CAS number
1531634-31-7
Molecular weight
324.25
Formula
C15H11F3N2O3
Solubility
DMSO : ≥ 43 mg/mL (132·61 mM)
InChIKey
JWCUSQCZMQIBMR-UHFFFAOYSA-N
Catalogue number
GC19023
Brand
GLPBIO
Computed properties PubChem CID 72706115 · XLogP 2.8 · TPSA 79.3 Ų · H-bond donors 2
XLogP
2.8
TPSA
79.3 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
3
Heavy atoms
23

SMILES CC1=NC(=CC=C1)NC(=O)C2=C(C=C(C=C2)C(F)(F)F)C(=O)O

Computed descriptors from PubChem (CID 72706115), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.