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Chemical structure of (R)-GNE-140

GC19012

(R)-GNE-140

Also known as (2R)-5-(2-chlorophenyl)sulfanyl-4-hydroxy-2-(4-morpholin-4-ylphenyl)-2-thiophen-3-yl-1,3-dihydropyridin-6-one

?A TRK kinase (TKI) inhibitor

ChemicalCAS2003234-63-5MW499.04FormulaC25H23ClN2O3S2
CAS number
2003234-63-5
Molecular weight
499.04
Formula
C25H23ClN2O3S2
Solubility
DMSO ： ≥ 14·43 mg/mL (28·92 mM);Water ： ＜ 0·1 mg/mL (insoluble)
InChIKey
SUFXXEIVBZJOAP-RUZDIDTESA-N
Catalogue number
GC19012
Brand
GLPBIO
Computed properties PubChem CID 121225870 · XLogP 4.8 · TPSA 115 Ų · H-bond donors 2
XLogP
4.8
TPSA
115 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
33

SMILES C1COCCN1C2=CC=C(C=C2)[C@]3(CC(=C(C(=O)N3)SC4=CC=CC=C4Cl)O)C5=CSC=C5

Computed descriptors from PubChem (CID 121225870), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.