Loading...
Chemical structure of NIBR0213

GC18895

NIBR0213

Also known as (2S)-2-[[4-[3-[[(1R)-1-(4-chloro-3-methylphenyl)ethyl]amino]phenyl]-2,6-dimethylbenzoyl]amino]propanoic acid

NIBR0213 is an orally bioavailable, potent, and selective antagonist of sphingosine-1-phosphate receptor-1 (S1P1) with IC50 values of 2·5 and 2·0 nM for the hS1P1 in a Ca2+ mobilization assay and GTPγS assay, respectively

ChemicalCAS1233332-14-3MW465FormulaC27H29ClN2O3
CAS number
1233332-14-3
Molecular weight
465
Formula
C27H29ClN2O3
Solubility
25mg/mL in DMSO, 25mg/mL in DMF, 25mg/mL in Ethanol
InChIKey
KYHUARFFBDLROH-MOPGFXCFSA-N
Catalogue number
GC18895
Brand
GLPBIO
Computed properties PubChem CID 59393720 · XLogP 6.4 · TPSA 78.4 Ų · H-bond donors 3
XLogP
6.4
TPSA
78.4 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
7
Heavy atoms
33

SMILES CC1=CC(=CC(=C1C(=O)N[C@@H](C)C(=O)O)C)C2=CC(=CC=C2)N[C@H](C)C3=CC(=C(C=C3)Cl)C

Computed descriptors from PubChem (CID 59393720), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.