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Chemical structure of G-5555

GC18720

G-5555

Also known as 8-[(5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methyl-2-pyridinyl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one

G-5555 is an inhibitor of p21-activated kinase 1 (PAK1; Ki = 3·7 nM), a non-receptor serine/threonine kinase involved in tumorigenesis

ChemicalCAS1648863-90-4MW493FormulaC25H25ClN6O3
CAS number
1648863-90-4
Molecular weight
493
Formula
C25H25ClN6O3
Solubility
DMSO ： ≥ 170 mg/mL (321·11 mM)
InChIKey
ZBCMHWUFWQFPLV-UHFFFAOYSA-N
Catalogue number
GC18720
Brand
GLPBIO
Computed properties PubChem CID 91664373 · XLogP 2.5 · TPSA 115 Ų · H-bond donors 2
XLogP
2.5
TPSA
115 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
5
Heavy atoms
35

SMILES CC1=NC(=CC=C1)C2=CC(=C(C=C2)C3=CC4=CN=C(N=C4N(C3=O)CC5OCC(CO5)N)NC)Cl

Computed descriptors from PubChem (CID 91664373), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.