GC18464
β-Secretase Inhibitor IV
Also known as 3-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl]-5-[methyl(methylsulfonyl)amino]-1-N-(1-phenylethyl)benzene-1,3-dicarboxamide
β-Secretase inhibitor IV is an inhibitor of β-site amyloid protein cleaving enzymes (BACE/β-secretase) 1 and 2 (IC50s = 15 and 230 nM for human BACE1 and 2, respectively)
ChemicalCAS797035-11-1MW578.7FormulaC31H38N4O5S
- CAS number
- 797035-11-1
- Molecular weight
- 578.7
- Formula
- C31H38N4O5S
- Solubility
- 10mg/mL in ethanol, 20mg/mL in DMSO or in DMF
- InChIKey
- VPNIQGRFZCTBEZ-BQTLCQCVSA-N
- Catalogue number
- GC18464
- Brand
- GLPBIO
Computed properties PubChem CID 71433892 · XLogP 3.6 · TPSA 136 Ų · H-bond donors 4
- XLogP
- 3.6
- TPSA
- 136 Ų
- H-bond donors
- 4
- H-bond acceptors
- 7
- Rotatable bonds
- 13
- Heavy atoms
- 41
SMILES CC(C1=CC=CC=C1)NC(=O)C2=CC(=CC(=C2)N(C)S(=O)(=O)C)C(=O)N[C@@H](CC3=CC=CC=C3)[C@@H](CNC4CC4)O
Computed descriptors from PubChem (CID 71433892), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il