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Chemical structure of PF-06281355

GC18256

PF-06281355

Also known as 2-[6-(2,5-dimethoxyphenyl)-4-oxo-2-sulfanylidenepyrimidin-1-yl]acetamide

PF-06281355 is a selective 2-thiouracil mechanism-based MPO inhibitor, used for treatment of vasculitic diseases

ChemicalCAS1435467-38-1MW321.4FormulaC14H15N3O4S
CAS number
1435467-38-1
Molecular weight
321.4
Formula
C14H15N3O4S
Solubility
DMF： 10mg/mL,DMF：PBS (pH 7·2) (1：1)： 0·5mg/mL,DMSO： 10mg/mL,Ethanol： 5mg/mL
InChIKey
LJBUZOGABRDGBR-UHFFFAOYSA-N
Catalogue number
GC18256
Brand
GLPBIO
Computed properties PubChem CID 71568997 · XLogP 0.3 · TPSA 126 Ų · H-bond donors 2
XLogP
0.3
TPSA
126 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
5
Heavy atoms
22

SMILES COC1=CC(=C(C=C1)OC)C2=CC(=O)NC(=S)N2CC(=O)N

Computed descriptors from PubChem (CID 71568997), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.