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Chemical structure of MK8353

GC18156

MK8353

Also known as (3S)-3-methylsulfanyl-1-[2-[4-[4-(1-methyl-1,2,4-triazol-3-yl)phenyl]-3,6-dihydro-2H-pyridin-1-yl]-2-oxoethyl]-N-[3-(6-propan-2-yloxy-3-pyridinyl)-1H-indazol-5-yl]pyrrolidine-3-carboxamide

Selective and orally available ERK1/2 inhibitor

ChemicalCAS1184173-73-6MW691.84FormulaC37H41N9O3S
CAS number
1184173-73-6
Molecular weight
691.84
Formula
C37H41N9O3S
Solubility
Soluble in DMSO
InChIKey
KPQQGHGDBBJGFA-QNGWXLTQSA-N
Catalogue number
GC18156
Brand
GLPBIO
Computed properties PubChem CID 58282870 · XLogP 4.3 · TPSA 159 Ų · H-bond donors 2
XLogP
4.3
TPSA
159 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
10
Heavy atoms
50

SMILES CC(C)OC1=NC=C(C=C1)C2=NNC3=C2C=C(C=C3)NC(=O)[C@@]4(CCN(C4)CC(=O)N5CCC(=CC5)C6=CC=C(C=C6)C7=NN(C=N7)C)SC

Computed descriptors from PubChem (CID 58282870), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.