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Chemical structure of Fatostatin A hydrobromide

GC18121

Fatostatin A hydrobromide

Also known as 4-(4-methylphenyl)-2-(2-propyl-4-pyridinyl)-1,3-thiazole;hydrobromide

Fatostatin A hydrobromide (125B11 hydrobromide), a specific inhibitor of SREBP activation, impairs the activation of SREBP-1 and SREBP-2· Fatostatin A hydrobromide binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs· Fatostatin A hydrobromide decreases the transcription of lipogenic genes in cells· Fatostatin A hydrobromide possesses antitumor properties, and lowers hyperglycemia in ob/ob mice

ChemicalCAS298197-04-3MW375.33FormulaC18H18N2S·HBr
CAS number
298197-04-3
Molecular weight
375.33
Formula
C18H18N2S·HBr
Solubility
≥ 19·76 mg/mL in DMSO, ≥ 5·02 mg/mL in EtOH
InChIKey
RJCFNQZVFUMORB-UHFFFAOYSA-N
Catalogue number
GC18121
Brand
GLPBIO
Computed properties PubChem CID 2850562 · TPSA 54 Ų · H-bond donors 1 · H-bond acceptors 3
TPSA
54 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
4
Heavy atoms
22

SMILES CCCC1=NC=CC(=C1)C2=NC(=CS2)C3=CC=C(C=C3)C.Br

Computed descriptors from PubChem (CID 2850562), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
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