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Chemical structure of Fasudil

GC13869

Fasudil

Also known as 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline

Fasudil (HA-1077; AT877) is a non-specific RhoA/ROCK inhibitor with a Ki of 0·33μM and an IC50 of 0·158μM for ROCK1, and IC50 of 4·58μM, 12·30μM, and 1·650μM for ROCK2, PKA, PKC, and PKG, respectively

ChemicalCAS103745-39-7MW291.37FormulaC14H17N3O2S
CAS number
103745-39-7
Molecular weight
291.37
Formula
C14H17N3O2S
Solubility
30mg/mL in DMSO; 50mg/mL in Water·
InChIKey
NGOGFTYYXHNFQH-UHFFFAOYSA-N
Catalogue number
GC13869
Brand
GLPBIO
Computed properties PubChem CID 3547 · XLogP 1 · TPSA 70.7 Ų · H-bond donors 1
XLogP
1
TPSA
70.7 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
2
Heavy atoms
20

SMILES C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3

Computed descriptors from PubChem (CID 3547), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.