Loading...
Chemical structure of PD173074

GC17943

PD173074

Also known as 1-tert-butyl-3-[2-[4-(diethylamino)butylamino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]urea

PD173074 is an ATP-competitive FGFR1 and VEGFR2 inhibitor with an IC50 value of 26nM and 100-200nM, respectively, showing higher selectivity for FGFR1 over PDGFR and c-Src

ChemicalCAS219580-11-7MW523.67FormulaC28H41N7O3
CAS number
219580-11-7
Molecular weight
523.67
Formula
C28H41N7O3
Solubility
≥ 26·1835mg/mL in DMSO, ≥ 108·4 mg/mL in EtOH with ultrasonic
InChIKey
DXCUKNQANPLTEJ-UHFFFAOYSA-N
Catalogue number
GC17943
Brand
GLPBIO
Computed properties PubChem CID 1401 · XLogP 4.5 · TPSA 114 Ų · H-bond donors 3
XLogP
4.5
TPSA
114 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
13
Heavy atoms
38

SMILES CCN(CC)CCCCNC1=NC2=NC(=C(C=C2C=N1)C3=CC(=CC(=C3)OC)OC)NC(=O)NC(C)(C)C

Computed descriptors from PubChem (CID 1401), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.