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Chemical structure of Xevinapant

GC17448

Xevinapant

Also listed as AT-406 (SM-406)

AT-406 (SM-406) (AT-406) is a potent and orally bioavailable Smac mimetic and an antagonist of IAPs, and it binds to XIAP, cIAP1, and cIAP2 proteins with Ki of 66·4, 1·9, and 5·1 nM, respectively

ChemicalCAS1071992-99-8MW561.71FormulaC32H43N5O4
CAS number
1071992-99-8
Molecular weight
561.71
Formula
C32H43N5O4
Solubility
≥ 27·65mg/mL in DMSO
InChIKey
LSXUTRRVVSPWDZ-MKKUMYSQSA-N
Catalogue number
GC17448
Brand
GLPBIO
Computed properties PubChem CID 25022340 · XLogP 3.1 · TPSA 111 Ų · H-bond donors 3
XLogP
3.1
TPSA
111 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
9
Heavy atoms
41

SMILES C[C@@H](C(=O)N[C@H]1CN(CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(C3=CC=CC=C3)C4=CC=CC=C4)C(=O)CC(C)C)NC

Computed descriptors from PubChem (CID 25022340), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
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