GC16904
PIK-75
Also known as N-[(E)-(6-bromoimidazo[1,2-a]pyridin-3-yl)methylideneamino]-N,2-dimethyl-5-nitrobenzenesulfonamide;hydrochloride
PIK-75 is a reversible DNA-PK and p110α-selective inhibitor, which inhibits DNA-PK, p110α and p110γ with IC50s of 2, 5·8 and 76 nM, respectively· PIK-75 inhibits p110α >200-fold more potently than p110β (IC50=1·3 μM)· PIK-75 induces apoptosis
ChemicalCAS372196-77-5MW488.74FormulaC16H14BrN5O4S·HCl
- CAS number
- 372196-77-5
- Molecular weight
- 488.74
- Formula
- C16H14BrN5O4S·HCl
- Solubility
- ≥ 8·15mg/mL in DMSO with gentle warming
- InChIKey
- VOUDEIAYNKZQKM-MYHMWQFYSA-N
- Catalogue number
- GC16904
- Brand
- GLPBIO
Computed properties PubChem CID 45265864 · TPSA 121 Ų · H-bond donors 1 · H-bond acceptors 7
- TPSA
- 121 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Rotatable bonds
- 4
- Heavy atoms
- 28
SMILES CC1=C(C=C(C=C1)[N+](=O)[O-])S(=O)(=O)N(C)/N=C/C2=CN=C3N2C=C(C=C3)Br.Cl
Computed descriptors from PubChem (CID 45265864), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il