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Chemical structure of PIK-III

GC14679

PIK-III

Also known as 4-(cyclopropylmethyl)-5-[2-(pyridin-4-ylamino)pyrimidin-4-yl]pyrimidin-2-amine

PIK-III is a potent and selective inhibitor of VPS34 with an IC50 of 18 nM

ChemicalCAS1383716-40-2MW319.36FormulaC17H17N7
CAS number
1383716-40-2
Molecular weight
319.36
Formula
C17H17N7
Solubility
≥ 31·9mg/mL in DMSO
InChIKey
XXSDLQLNIVFIJI-UHFFFAOYSA-N
Catalogue number
GC14679
Brand
GLPBIO
Computed properties PubChem CID 67983123 · XLogP 2 · TPSA 103 Ų · H-bond donors 2
XLogP
2
TPSA
103 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
24

SMILES C1CC1CC2=NC(=NC=C2C3=NC(=NC=C3)NC4=CC=NC=C4)N

Computed descriptors from PubChem (CID 67983123), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.