Loading...
Chemical structure of AST-1306 TsOH

GC15669

AST-1306 TsOH

Also known as N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]prop-2-enamide;4-methylbenzenesulfonic acid

AST-1306 TsOH (AST-1306 (TsOH)) is an orally active and irreversible EGFR and ErbB2 inhibitor with IC50s of 0·5 and 3 nM, respectively· AST-1306 TsOH also inhibits ErbB4 with an IC50 of 0·8 nM· AST-1306 TsOH is an anilino-quinazoline compound and has anti-cancer activity

ChemicalCAS1050500-29-2MW621.08FormulaC31H26ClFN4O5S
CAS number
1050500-29-2
Molecular weight
621.08
Formula
C31H26ClFN4O5S
Solubility
DMF： 25 mg/ml,DMF：PBS (pH 7·2) (1：3)： 0·25 mg/ml,DMSO： 20 mg/ml,Ethanol： 1 mg/ml
InChIKey
ZMUKJEHWLJBODV-UHFFFAOYSA-N
Catalogue number
GC15669
Brand
GLPBIO
Computed properties PubChem CID 25027665 · TPSA 139 Ų · H-bond donors 3 · H-bond acceptors 9
TPSA
139 Ų
H-bond donors
3
H-bond acceptors
9
Rotatable bonds
8
Heavy atoms
43

SMILES CC1=CC=C(C=C1)S(=O)(=O)O.C=CC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=C(C=C3)OCC4=CC(=CC=C4)F)Cl

Computed descriptors from PubChem (CID 25027665), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.