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Chemical structure of Rolapitant

GC15449

Rolapitant

Also known as (5S,8S)-8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-1,9-diazaspiro[4.5]decan-2-one

Orally active neurokinin NK1 receptor antagonist

ChemicalCAS552292-08-7MW500.48FormulaC25H26F6N2O2
CAS number
552292-08-7
Molecular weight
500.48
Formula
C25H26F6N2O2
Solubility
DMF： 25 mg/ml,DMF：PBS(pH7·2) (1：2)： 0·33 mg/ml,DMSO： 16 mg/ml,Ethanol： 3 mg/ml
InChIKey
FIVSJYGQAIEMOC-ZGNKEGEESA-N
Catalogue number
GC15449
Brand
GLPBIO
Computed properties PubChem CID 10311306 · XLogP 4.4 · TPSA 50.4 Ų · H-bond donors 2
XLogP
4.4
TPSA
50.4 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
5
Heavy atoms
35

SMILES C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)OC[C@]2(CC[C@]3(CCC(=O)N3)CN2)C4=CC=CC=C4

Computed descriptors from PubChem (CID 10311306), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.