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Chemical structure of PD 166326

GC15314

PD 166326

Also known as 6-(2,6-dichlorophenyl)-2-[3-(hydroxymethyl)anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one

receptor tyrosine kinases inhibitor

ChemicalCAS185039-91-2MW427.3FormulaC21H16Cl2N4O2
CAS number
185039-91-2
Molecular weight
427.3
Formula
C21H16Cl2N4O2
Solubility
≤25mg/ml in DMSO;25mg/ml in dimethyl formamide
InChIKey
ZIQFYVPVJZEOFS-UHFFFAOYSA-N
Catalogue number
GC15314
Brand
GLPBIO
Computed properties PubChem CID 447700 · XLogP 4 · TPSA 78.4 Ų · H-bond donors 2
XLogP
4
TPSA
78.4 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
29

SMILES CN1C2=NC(=NC=C2C=C(C1=O)C3=C(C=CC=C3Cl)Cl)NC4=CC=CC(=C4)CO

Computed descriptors from PubChem (CID 447700), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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