GC50045
PD 166285 dihydrochloride
Also known as 6-(2,6-dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one;dihydrochloride
PD 166285 dihydrochloride, a substrate of P-gp, is a WEE1 inhibitor and a weak Myt1 inhibitor with IC50 values of 24 and 72 nM, respectively· PD 166285 dihydrochloride exhibits an IC50 of 3·433 μM for Chk1
ChemicalCAS212391-63-4MW585.35FormulaC26H27Cl2N5O2·2HCl
- CAS number
- 212391-63-4
- Molecular weight
- 585.35
- Formula
- C26H27Cl2N5O2·2HCl
- Solubility
- Soluble in DMSO
- InChIKey
- NADLBPWBFGTESN-UHFFFAOYSA-N
- Catalogue number
- GC50045
- Brand
- GLPBIO
Computed properties PubChem CID 9916391 · TPSA 70.6 Ų · H-bond donors 3 · H-bond acceptors 6
- TPSA
- 70.6 Ų
- H-bond donors
- 3
- H-bond acceptors
- 6
- Rotatable bonds
- 9
- Heavy atoms
- 37
SMILES CCN(CC)CCOC1=CC=C(C=C1)NC2=NC=C3C=C(C(=O)N(C3=N2)C)C4=C(C=CC=C4Cl)Cl.Cl.Cl
Computed descriptors from PubChem (CID 9916391), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il