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Chemical structure of Tivozanib (hydrate)

GC15280

Tivozanib (hydrate)

Also known as 1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(5-methyl-1,2-oxazol-3-yl)urea;hydrate

VEGFR inhibitor, orally available

ChemicalCAS682745-40-0MW472.9FormulaC22H19ClN4O5 • H2O
CAS number
682745-40-0
Molecular weight
472.9
Formula
C22H19ClN4O5 • H2O
Solubility
≤25mg/ml in DMSO;30mg/ml in dimethyl formamide
InChIKey
VTWZGSZTIGEYIC-UHFFFAOYSA-N
Catalogue number
GC15280
Brand
GLPBIO
Computed properties PubChem CID 71433801 · TPSA 109 Ų · H-bond donors 3 · H-bond acceptors 8
TPSA
109 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
6
Heavy atoms
33

SMILES CC1=CC(=NO1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)Cl.O

Computed descriptors from PubChem (CID 71433801), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
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