Loading...
Chemical structure of Tie2 kinase inhibitor

GC14898

Tie2 kinase inhibitor

Also known as 4-[4-(6-methoxynaphthalen-2-yl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine

Tie2 kinase inhibitor is a reversible and selective inhibitor of Tie2 with an IC50 of 250 nM

ChemicalCAS948557-43-5MW439.53FormulaC26H21N3O2S
CAS number
948557-43-5
Molecular weight
439.53
Formula
C26H21N3O2S
Solubility
≥ 22mg/mL in DMSO
InChIKey
SINQIEAULQKUPD-UHFFFAOYSA-N
Catalogue number
GC14898
Brand
GLPBIO
Computed properties PubChem CID 23625762 · XLogP 4.3 · TPSA 87.1 Ų · H-bond donors 1
XLogP
4.3
TPSA
87.1 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
5
Heavy atoms
32

SMILES COC1=CC2=C(C=C1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)S(=O)C)C5=CC=NC=C5

Computed descriptors from PubChem (CID 23625762), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.