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Chemical structure of WYE-125132 (WYE-132)

GC14675

WYE-125132 (WYE-132)

Also known as 1-[4-[1-(1,4-dioxaspiro[4.5]decan-8-yl)-4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)pyrazolo[5,4-d]pyrimidin-6-yl]phenyl]-3-methylurea

WYE-125132 (WYE-132) (WYE-125132) is a highly potent, ATP-competitive, and specific mTOR kinase inhibitor (IC50: 0·19±0·07 nM; >5,000-fold selective versus PI3Ks)· WYE-125132 (WYE-132) (WYE-125132) inhibits mTORC1 and mTORC2

ChemicalCAS1144068-46-1MW519.61FormulaC27H33N7O4
CAS number
1144068-46-1
Molecular weight
519.61
Formula
C27H33N7O4
Solubility
≥ 13mg/mL in DMSO
InChIKey
QLHHRYZMBGPBJG-UHFFFAOYSA-N
Catalogue number
GC14675
Brand
GLPBIO
Computed properties PubChem CID 25260757 · XLogP 2.2 · TPSA 116 Ų · H-bond donors 2
XLogP
2.2
TPSA
116 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
4
Heavy atoms
38

SMILES CNC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=NN3C4CCC5(CC4)OCCO5)C(=N2)N6CC7CCC(C6)O7

Computed descriptors from PubChem (CID 25260757), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.