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Chemical structure of WYE 672

GB40415

WYE 672

Also known as 3-methyl-2-[4-(3-methylsulfonylphenyl)phenyl]-5-(trifluoromethyl)quinoxaline

A tissue selective liver X receptor (LXR) agonist; WYE672 showed potent binding affinity to LXRβ (IC50 = 53 nM), it had little binding affinity for LXRα (IC50 >1·0 μM)

ChemicalCAS1221265-37-7MW442.45FormulaC23H17F3N2O2S
CAS number
1221265-37-7
Molecular weight
442.45
Formula
C23H17F3N2O2S
InChIKey
YKGVGRQMFLSEFJ-UHFFFAOYSA-N
Catalogue number
GB40415
Brand
GLPBIO
Computed properties PubChem CID 46206336 · XLogP 5 · TPSA 68.3 Ų · H-bond donors 0
XLogP
5
TPSA
68.3 Ų
H-bond donors
0
H-bond acceptors
7
Rotatable bonds
3
Heavy atoms
31

SMILES CC1=NC2=C(C=CC=C2N=C1C3=CC=C(C=C3)C4=CC(=CC=C4)S(=O)(=O)C)C(F)(F)F

Computed descriptors from PubChem (CID 46206336), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.