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Chemical structure of Masitinib

GC13410

Masitinib

Also listed as Masitinib (AB1010)

Masitinib (AB1010) (AB1010) is a potent, orally bioavailable, and selective inhibitor of c-Kit (IC50=200 nM for human recombinant c-Kit)· It also inhibits PDGFRα/β (IC50s=540/800 nM), Lyn (IC50= 510 nM for LynB), Lck, and, to a lesser extent, FGFR3 and FAK· Masitinib (AB1010) (AB1010) has anti-proliferative, pro-apoptotic activity and low toxicity

ChemicalCAS790299-79-5MW498.64FormulaC28H30N6OS
CAS number
790299-79-5
Molecular weight
498.64
Formula
C28H30N6OS
Solubility
≥ 24·95mg/mL in DMSO
InChIKey
WJEOLQLKVOPQFV-UHFFFAOYSA-N
Catalogue number
GC13410
Brand
GLPBIO
Computed properties PubChem CID 10074640 · XLogP 4.3 · TPSA 102 Ų · H-bond donors 2
XLogP
4.3
TPSA
102 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
36

SMILES CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC(=CS4)C5=CN=CC=C5

Computed descriptors from PubChem (CID 10074640), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.