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Chemical structure of EPZ004777

GC13383

EPZ004777

Also known as 1-[3-[[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxyoxolan-2-yl]methyl-propan-2-ylamino]propyl]-3-(4-tert-butylphenyl)urea

EPZ004777, as a potent epigenetic modulators, can reverse TGF-β1 induced T regulatory cells and may be used to treat diverse immune disorders

ChemicalCAS1338466-77-5MW539.67FormulaC28H41N7O4
CAS number
1338466-77-5
Molecular weight
539.67
Formula
C28H41N7O4
Solubility
≥ 27 mg/mL in DMSO, ≥ 94·6 mg/mL in EtOH with ultrasonic
InChIKey
WXRGFPHDRFQODR-ICLZECGLSA-N
Catalogue number
GC13383
Brand
GLPBIO
Computed properties PubChem CID 56962336 · XLogP 2.4 · TPSA 151 Ų · H-bond donors 5
XLogP
2.4
TPSA
151 Ų
H-bond donors
5
H-bond acceptors
8
Rotatable bonds
10
Heavy atoms
39

SMILES CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)C[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=CC4=C(N=CN=C43)N)O)O

Computed descriptors from PubChem (CID 56962336), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.