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Chemical structure of PR-619

GC13208

PR-619

Also known as (2,6-diamino-5-thiocyanato-3-pyridinyl) thiocyanate

PR-619 is a broad-spectrum DUB (deubiquitinating enzyme) inhibitor· PR-619 has demonstrated robust DUB inhibitory activity (5-20 µM) and growth inhibitory activity with IC50 of 2 µM in HEK 293T cells

ChemicalCAS2645-32-1MW223.28FormulaC7H5N5S2
CAS number
2645-32-1
Molecular weight
223.28
Formula
C7H5N5S2
Solubility
≥ 11·15mg/mL in DMSO
InChIKey
ZXOBLNBVNROVLC-UHFFFAOYSA-N
Catalogue number
GC13208
Brand
GLPBIO
Computed properties PubChem CID 2817763 · XLogP 1.3 · TPSA 163 Ų · H-bond donors 2
XLogP
1.3
TPSA
163 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
2
Heavy atoms
14

SMILES C1=C(C(=NC(=C1SC#N)N)N)SC#N

Computed descriptors from PubChem (CID 2817763), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.