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Chemical structure of Binimetinib

GC12843

Binimetinib

Also listed as MEK162 (ARRY-162, ARRY-438162)

MEK162 (ARRY-162, ARRY-438162) (MEK162) is an oral and selective MEK1/2 inhibitor· MEK162 (ARRY-162, ARRY-438162) (MEK162) inhibits MEK with an IC50 of 12 nM

ChemicalCAS606143-89-9MW441.23FormulaC17H15BrF2N4O3
CAS number
606143-89-9
Molecular weight
441.23
Formula
C17H15BrF2N4O3
Solubility
2mg/ml in DMSO
InChIKey
ACWZRVQXLIRSDF-UHFFFAOYSA-N
Catalogue number
GC12843
Brand
GLPBIO
Computed properties PubChem CID 10288191 · XLogP 3.1 · TPSA 88.4 Ų · H-bond donors 3
XLogP
3.1
TPSA
88.4 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
27

SMILES CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)F)C(=O)NOCCO

Computed descriptors from PubChem (CID 10288191), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.