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Chemical structure of MEL24

GC69447

MEL24

Also known as 1,3-dimethyl-5-(2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)-1,3-diazinane-2,4,6-trione

MEL24 is a type of Mdm2 E3 ligase inhibitor that reduces cell survival in a p53-dependent manner and increases sensitivity to DNA damaging agents· It is used for in vitro anti-tumor research

ChemicalCAS642072-48-8MW326.35FormulaC17H18N4O3
CAS number
642072-48-8
Molecular weight
326.35
Formula
C17H18N4O3
InChIKey
FOUOSAVQDWJOGI-UHFFFAOYSA-N
Catalogue number
GC69447
Brand
GLPBIO
Computed properties PubChem CID 71451689 · XLogP 0.5 · TPSA 85.5 Ų · H-bond donors 2
XLogP
0.5
TPSA
85.5 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
1
Heavy atoms
24

SMILES CN1C(=O)C(C(=O)N(C1=O)C)C2C3=C(CCN2)C4=CC=CC=C4N3

Computed descriptors from PubChem (CID 71451689), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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