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Chemical structure of LGK-974

GC12392

LGK-974

Also known as 2-[5-methyl-6-(2-methyl-4-pyridinyl)-3-pyridinyl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide

LGK-974 is a potent and specific inhibitor of Porcupine (PORCN)

ChemicalCAS1243244-14-5MW396.44FormulaC23H20N6O
CAS number
1243244-14-5
Molecular weight
396.44
Formula
C23H20N6O
Solubility
≥ 19·8mg/mL in DMSO
InChIKey
XXYGTCZJJLTAGH-UHFFFAOYSA-N
Catalogue number
GC12392
Brand
GLPBIO
Computed properties PubChem CID 46926973 · XLogP 1.8 · TPSA 93.6 Ų · H-bond donors 1
XLogP
1.8
TPSA
93.6 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
30

SMILES CC1=CC(=CN=C1C2=CC(=NC=C2)C)CC(=O)NC3=NC=C(C=C3)C4=NC=CN=C4

Computed descriptors from PubChem (CID 46926973), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.