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Chemical structure of Tiplasinin

GC12387

Tiplasinin

Also listed as Tiplaxtinin(PAI-039)

Tiplaxtinin(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2·7 μM

ChemicalCAS393105-53-8MW439.38FormulaC24H16F3NO4
CAS number
393105-53-8
Molecular weight
439.38
Formula
C24H16F3NO4
Solubility
≥ 17·6mg/mL in DMSO
InChIKey
ODXQFEWQSHNQNI-UHFFFAOYSA-N
Catalogue number
GC12387
Brand
GLPBIO
Computed properties PubChem CID 6450819 · XLogP 5.8 · TPSA 68.5 Ų · H-bond donors 1
XLogP
5.8
TPSA
68.5 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
32

SMILES C1=CC=C(C=C1)CN2C=C(C3=C2C=CC(=C3)C4=CC=C(C=C4)OC(F)(F)F)C(=O)C(=O)O

Computed descriptors from PubChem (CID 6450819), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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